Why Illumina’s investment in MyOme could reset expectations for genome-based prevention

Why Illumina’s investment in MyOme could reset expectations for genome-based prevention

Illumina, Inc. and MyOme, Inc. have announced a new strategic collaboration, including an equity investment by Illumina to support MyOme’s upcoming Proactive Health (MPH) Trial. The large-scale clinical study, expected to begin in 2026, will evaluate the impact of artificial intelligence-integrated whole-genome sequencing on chronic disease prevention and cost savings across the U.S. healthcare system. […]

Is InstaMed’s oral peptide strip the needle-free breakthrough peptide delivery has been waiting for?

Is InstaMed’s oral peptide strip the needle-free breakthrough peptide delivery has been waiting for?

InstaMed Pharmaceuticals has reported rapid commercial traction for its InstaRelease oral dissolving strip, a patented non-injectable peptide delivery technology. The company announced a 300 percent month-over-month sales increase since its May 2025 launch and shared results from a double-blind pharmacokinetic study validating buccal absorption of glutathione as an effective alternative to traditional injection. The platform […]

Can B-cell depletion change how we treat generalized myasthenia gravis?

Can B-cell depletion change how we treat generalized myasthenia gravis?

Amgen has received approval from the United States Food and Drug Administration for Uplizna (inebilizumab-cdon) to treat adults with generalized myasthenia gravis who are anti-acetylcholine receptor or anti-muscle specific tyrosine kinase antibody positive. The greenlight makes Uplizna the first and only CD19-targeted B cell therapy approved for this patient population, introducing a twice-yearly dosing regimen […]

What Orphalan’s Orphelia Pharma acquisition reveals about the next phase of rare pediatric drug consolidation

What Orphalan’s Orphelia Pharma acquisition reveals about the next phase of rare pediatric drug consolidation

Orphalan, the international pharmaceutical company known for developing orphan drugs, has announced the acquisition of Orphelia Pharma, a specialist in rare and severe pediatric diseases. The deal enhances Orphalan’s position in the European rare disease market, particularly within pediatric neurology and oncology, and signals a strategic pivot toward deeper vertical integration in pediatric formulations and […]

Why are “retired proteins” the hottest new targets in cancer immunotherapy research?

Why are “retired proteins” the hottest new targets in cancer immunotherapy research?

Few ideas have captivated both the scientific imagination and biotech investment flows quite like the cancer vaccine. For decades, the industry narrative was full of hope—and disappointment. The graveyard of failed trials stretches from Dendreon’s Provenge to once-hyped peptide and dendritic cell platforms. For every announcement of an “immune breakthrough,” there seemed to be a […]

Can Alphyn’s multi-target strategy disrupt dermatology? Why Zabalafin’s $25m backing matters

Can Alphyn’s multi-target strategy disrupt dermatology? Why Zabalafin’s $25m backing matters

Alphyn Biologics has secured $25 million in a twice-oversubscribed Series B financing round to support its clinical pipeline for dermatologic conditions. The funding will enable the company to advance a global Phase 2b trial of its lead asset, Zabalafin Hydrogel, for atopic dermatitis, while also launching a second Phase 2 program for molluscum contagiosum virus. […]

Can Actinium’s ATNM-400 radiotherapy reshape treatment for resistant breast cancer?

Can Actinium’s ATNM-400 radiotherapy reshape treatment for resistant breast cancer?

Actinium Pharmaceuticals, Inc. has presented new preclinical data for its alpha-particle radiotherapy candidate ATNM-400 at the 2025 San Antonio Breast Cancer Symposium (SABCS), highlighting potent anti-tumor activity across hormone receptor–positive, triple-negative, and therapy-resistant breast cancer models. The findings suggest that ATNM-400 could become a differentiated treatment option for patients with tumors that have progressed after […]

Can Sanyou Biopharmaceuticals and KanryBio Biotechnology disrupt the global companion diagnostics market?

Can Sanyou Biopharmaceuticals and KanryBio Biotechnology disrupt the global companion diagnostics market?

Sanyou Biopharmaceuticals (Shanghai) Co., Ltd. and Wenzhou KanryBio Biotechnology Co., Ltd. have entered into a strategic collaboration focused on co-developing high-value reagents and products for biomarker assay kits. Announced on December 10, 2025, this partnership aims to combine Sanyou Biopharmaceuticals’ global leadership in AI-driven molecular discovery with KanryBio Biotechnology’s capabilities in kit product development and […]

Can Eli Lilly’s Inluriyo outpace rivals in ESR1-mutated breast cancer after EMBER-3?

Can Eli Lilly’s Inluriyo outpace rivals in ESR1-mutated breast cancer after EMBER-3?

Eli Lilly and Company has released updated Phase 3 EMBER-3 results for Inluriyo, also known as imlunestrant, its oral estrogen receptor antagonist, in patients with estrogen receptor-positive and human epidermal growth factor receptor 2–negative advanced or metastatic breast cancer. These new data, presented at the 2025 San Antonio Breast Cancer Symposium and published in Annals […]

FDA approval gives J&J’s AKEEGA a first-mover edge in BRCA2-mutated metastatic prostate cancer

FDA approval gives J&J’s AKEEGA a first-mover edge in BRCA2-mutated metastatic prostate cancer

Johnson & Johnson (J&J) announced on December 12, 2025, that the U.S. Food and Drug Administration approved AKEEGA, a dual-action tablet combining niraparib and abiraterone acetate, alongside prednisone, for treating BRCA2-mutated metastatic castration-sensitive prostate cancer. The regulatory nod, based on the pivotal AMPLITUDE trial, makes AKEEGA the first precision medicine combination approved for this high-risk […]