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ctDNA

Medical Devices & Diagnostics

Why Natera’s Diakonos Oncology collaboration matters for ctDNA-guided cancer drug development

Natera’s Signatera will track molecular response in a refractory melanoma trial. Find out why ctDNA is becoming central to oncology R&D.

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Pharma & Biotech

Why AstraZeneca’s EMERALD-3 and SERENA-6 data could influence future standards of cancer care

Could AstraZeneca’s latest ASCO 2026 cancer data reshape future treatment sequencing in liver and breast oncology? Read the full analysis.

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Medical Devices & Diagnostics

Genentech’s Tecentriq decision puts Natera’s Signatera at the centre of precision bladder cancer care

Bladder cancer treatment is becoming more selective. Tecentriq’s ctDNA-guided approval may redefine who gets adjuvant immunotherapy.

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Medical Devices & Diagnostics

How Exact Sciences is building a multi-platform cancer diagnostics case at AACR 2026

Exact Sciences presents Oncodetect MRD and Cancerguard MCED data at AACR 2026. Analysis of what the new TNBC and multi-biomarker classifier findings mean for clinical adoption.

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Pharma & Biotech

Can ctDNA-guided bladder preservation become viable after Signatera’s ASCO GU data?

New ASCO GU data shows how Signatera ctDNA may guide bladder preservation and adjuvant therapy decisions in muscle-invasive bladder cancer. Read the analysis.

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Pharma & Biotech

Is Avenzo’s AVZO-021 the next big player in HR+/HER2- metastatic breast cancer?

Avenzo shares Phase 1 data on CDK2 inhibitor AVZO-021 in HR+/HER2- breast cancer. Find out what it means for post-CDK4/6 resistance strategies in 2025.

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Medical Devices & Diagnostics

What the TRACERx study reveals about Personalis’ MRD technology in NSCLC

Personalis, Inc. has reported pivotal findings from its NeXT Personal assay in a new Cell publication, highlighting the test’s ability to detect molecular residual disease in stage I to III non-small cell lung cancer. The study, part of the TRACERx initiative and led by Professor Charles Swanton of the Francis Crick Institute and University College

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Medical Devices & Diagnostics

Exact Sciences unveils key Oncodetect results in TNBC: Is this a reimbursement turning point?

Exact Sciences Corporation has presented first-time clinical results for its Oncodetect molecular residual disease (MRD) test in early triple-negative breast cancer (TNBC), showcasing a strong correlation between circulating tumor DNA (ctDNA) detection and recurrence risk following neoadjuvant therapy and surgery. The results, drawn from a 147-patient cohort in the NSABP B-59 substudy, were unveiled at

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Pharma & Biotech

Will TTX-MC138 in ctDNA-positive patients provide a new model for MRD intervention?

TransCode Therapeutics, Inc. and Quantum Leap Healthcare Collaborative have launched a Phase 2a dose-expansion trial of TTX-MC138, an RNA-targeting therapeutic aimed at preventing metastatic recurrence in colorectal cancer patients who are ctDNA-positive after standard curative treatment. The trial is part of the PRE-I-SPY platform and will enroll up to 45 patients in early 2026, led

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Medical Devices & Diagnostics

Can TrilliumBiO and Oncobit make MRD monitoring standard for uveal melanoma in the U.S.?

TrilliumBiO and Oncobit launch a ctDNA-based monitoring platform for uveal melanoma in the U.S. Learn how this could change rare cancer care in 2026.

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