Business, energy, technology, markets and global industry news from Business News Today

hepatocellular carcinoma

Pharma & Biotech

Pilatus Biosciences doses first Hong Kong patient in PLT012 liver cancer trial

Pilatus Biosciences has dosed its first patient in Hong Kong in the ongoing Phase 1 study of PLT012, an investigational CD36-targeting antibody for advanced cancers. The new hepatocellular carcinoma cohort will examine safety, early clinical activity and biomarkers associated with tumor metabolism and immune suppression.

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Pharma & Biotech

AbelZeta and AstraZeneca study identifies GPC3 loss as a potential C-CAR031 resistance mechanism

AbelZeta’s C-CAR031 study shows a 44.4% response rate in advanced liver cancer, but durability and resistance remain key tests.

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Pharma & Biotech

Could Confluence Genetics’ Cas-CLEAR platform open a new path for liver cancer therapy?

Confluence Genetics launches Cas-CLEAR, a Cas12a2 CRISPR platform designed to kill mutation-bearing cancer cells. Explore the evidence and risks.

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Pharma & Biotech

Oricell’s ASCO 2026 liver cancer data put GPC3 CAR-T back in the spotlight

Find out how Oricell’s Ori-C101 CAR-T data could reshape expectations for late-line liver cancer treatment after ASCO 2026.

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Pharma & Biotech

Why AstraZeneca’s EMERALD-3 and SERENA-6 data could influence future standards of cancer care

Could AstraZeneca’s latest ASCO 2026 cancer data reshape future treatment sequencing in liver and breast oncology? Read the full analysis.

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Pharma & Biotech

Can Agenus turn botensilimab and balstilimab into a serious post-ICI liver cancer contender?

Post-ICI liver cancer has few strong options. Agenus’ BOT plus BAL data raise the next question: can durability survive larger trials?

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Pharma & Biotech

FDA RMAT status puts Rznomics’ RNA editing platform under a brighter clinical spotlight

RNA editing just gained a liver cancer spotlight. Rznomics must now prove RZ-001 can turn early response signals into durable clinical value.

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Pharma & Biotech

Can Rznomics turn RZ-001 into a breakthrough therapy for hepatocellular carcinoma?

Rznomics reported interim RZ-001 liver cancer data at AACR 2026. Read why the efficacy and safety signals could matter for hepatocellular carcinoma.

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Pharma & Biotech

Can Abbisko Therapeutics turn irpagratinib into the first approved FGFR4 therapy for hepatocellular carcinoma?

Abbisko Therapeutics won EMA orphan drug designation for irpagratinib in liver cancer. Read what this changes for FGFR4-targeted therapy.

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Pharma & Biotech

Can targeting CD36 reshape hepatocellular carcinoma immunotherapy? Pilatus Biosciences takes first step

Pilatus Biosciences earns FDA Fast Track for PLT012 in liver cancer. Read why CD36 targeting could reshape immunotherapy development.

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