AusperBio’s AHB‑137 enters final testing phase in HBeAg-negative chronic hepatitis B patients

AusperBio’s AHB‑137 enters final testing phase in HBeAg-negative chronic hepatitis B patients

AusperBio Therapeutics has completed patient enrollment in its Phase III AUSHINE trial evaluating AHB‑137 for the treatment of HBeAg-negative chronic hepatitis B. The randomized, double-blind, multicenter study, launched in China under regulatory clearance from the Center for Drug Evaluation, surpassed its initial enrollment goal with over 570 patients enrolled within five months. AHB‑137 is being […]

Proton therapy delivers survival gain in head and neck cancer: Could this Lancet trial shift payer and policy resistance?

Proton therapy delivers survival gain in head and neck cancer: Could this Lancet trial shift payer and policy resistance?

A new phase III clinical trial published in The Lancet has shown that proton therapy significantly improves overall survival and reduces treatment-related toxicities in patients with oropharyngeal cancers compared to traditional photon-based radiation. Conducted across 21 U.S. institutions and led by researchers at the University of Texas MD Anderson Cancer Center, the study is the […]

Can Akeso’s cadonilimab unlock PD-L1-agnostic immunotherapy for gastric cancer patients?

Can Akeso’s cadonilimab unlock PD-L1-agnostic immunotherapy for gastric cancer patients?

Akeso Inc. has secured clearance from the United States Food and Drug Administration to initiate COMPASSION-37, a global Phase III trial evaluating cadonilimab, a first-in-class PD-1/CTLA-4 bispecific antibody, as part of a first-line treatment regimen for HER2-negative, unresectable or metastatic gastric and gastroesophageal junction adenocarcinoma. The randomized, multicenter trial will compare cadonilimab plus chemotherapy against […]