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Home»Posts tagged with»cardiometabolic disease

Can enicepatide and petrelintide help Genentech build a differentiated obesity franchise?

By Pallavi Madhiraju on June 1, 2026   Pharma & Biotech  

Can enicepatide and petrelintide help Genentech build a differentiated obesity franchise?

Genentech advances enicepatide and petrelintide obesity data at ADA 2026. Find out why Roche’s strategy matters now.

Can Scribe Therapeutics make one-dose LDL-C lowering a practical CRISPR frontier?

By Pallavi Madhiraju on May 29, 2026   Pharma & Biotech  

Can Scribe Therapeutics make one-dose LDL-C lowering a practical CRISPR frontier?

Find out how Scribe Therapeutics’ STX-1150 could reshape long-acting LDL-C lowering through CRISPR-based epigenetic silencing.

Scribe Therapeutics brings specificity challenge into focus for CRISPR cardiometabolic drugs

By Pallavi Madhiraju on May 18, 2026   Pharma & Biotech  

Scribe Therapeutics brings specificity challenge into focus for CRISPR cardiometabolic drugs

CRISPR can lower cholesterol. The harder test is whether Scribe can make durability, precision, and scalability work in common disease.

GSK’s $1bn SiranBio pact raises the stakes in extrahepatic siRNA delivery

By Pallavi Madhiraju on May 9, 2026   Pharma & Biotech  

GSK’s $1bn SiranBio pact raises the stakes in extrahepatic siRNA delivery

GLP-1 drugs dominate obesity. GSK is betting SiranBio’s SA030 can attack visceral fat risk from a different angle.

Why MetaVia’s higher-dose titration strategy could matter more than the first-patient milestone itself

By Pallavi Madhiraju on April 11, 2026   Pharma & Biotech  

Why MetaVia’s higher-dose titration strategy could matter more than the first-patient milestone itself

MetaVia has started higher-dose testing for DA-1726 in obesity. Read what this means for tolerability, competition, and the next clinical milestone.

Can Merck’s enlicitide decanoate become the oral PCSK9 breakthrough cholesterol care has been waiting for?

By Pallavi Madhiraju on March 31, 2026   Pharma & Biotech  

Can Merck’s enlicitide decanoate become the oral PCSK9 breakthrough cholesterol care has been waiting for?

Merck’s enlicitide decanoate beat oral rivals in Phase 3. Read what this could change for cholesterol care, PCSK9 adoption, and market strategy.

Can Merck expand WINREVAIR beyond pulmonary arterial hypertension after CADENCE data?

By Pallavi Madhiraju on March 30, 2026   Pharma & Biotech  

Can Merck expand WINREVAIR beyond pulmonary arterial hypertension after CADENCE data?

Can Merck turn WINREVAIR’s CADENCE data into a new treatment path in CpcPH-HFpEF? Read the full analysis of what changes next.

Scribe Therapeutics deepens in vivo CRISPR validation with second Eli Lilly collaboration milestone

By Pallavi Madhiraju on February 18, 2026   Pharma & Biotech  

Scribe Therapeutics deepens in vivo CRISPR validation with second Eli Lilly collaboration milestone

Scribe Therapeutics hits a second in vivo CRISPR milestone with Eli Lilly. Explore what this changes for gene editing platforms and future therapies.

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