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EVO756-MIG001

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Evommune’s investigational oral MRGPRX2 inhibitor EVO756 enters a Phase 2b migraine prevention trial, testing a new neuroimmune approach after the programme’s urticaria setback. Representative image.

Pharma & Biotech

Can MRGPRX2 inhibition prevent migraine? Evommune’s EVO756 enters Phase 2b study

by Pallavi Madhiraju
August 2, 2026
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Evommune begins a Phase 2b EVO756 migraine trial after a urticaria setback, testing whether MRGPRX2 inhibition can deliver preventive benefit.

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Representative image of biopharma laboratory research. Gilead Sciences and Merck’s latest Phase 3 updates highlight the promise of once-weekly HIV treatment with islatravir and lenacapavir, while raising fresh questions over Trodelvy’s lung cancer expansion strategy.

Pharma & Biotech

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clinical trials Eli Lilly and Company European Medicines Agency FDA FDA approval immuno-oncology immunotherapy Inc. Johnson & Johnson medical devices oncology precision oncology rare disease U.S. Food and Drug Administration United States Food and Drug Administration

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