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PROTAC

Pharma & Biotech

How Arvinas and Pfizer’s VEPPANU approval tests the commercial future of PROTAC drugs

Arvinas Inc., with partner Pfizer Inc., has received U.S. Food and Drug Administration approval for VEPPANU, also known as vepdegestrant, for adults with estrogen receptor-positive, human epidermal growth factor receptor 2-negative, ESR1-mutated advanced or metastatic breast cancer after disease progression following at least one line of endocrine therapy. The approval gives the oncology market its

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Pharma & Biotech

NiKang Therapeutics unveils NKT5097 as dual CDK2/4 degrader for solid tumor strategy

NiKang Therapeutics’ NKT5097 enters Phase 1 as a dual CDK2/4 degrader aiming to overcome breast cancer resistance. Explore what this strategy changes.

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