FDA fast track for Argo Biopharma’s BW-20805 siRNA puts HAE’s next competitive battleground in focus

FDA fast track for Argo Biopharma’s BW-20805 siRNA puts HAE’s next competitive battleground in focus

Argo Biopharmaceutical Co., Ltd. (Argo Biopharma), a Shanghai-based clinical-stage RNA interference therapeutics company, has received Fast Track Designation from the U.S. Food and Drug Administration for BW-20805, its investigational small interfering RNA therapy targeting prekallikrein for the prevention of hereditary angioedema attacks. The designation comes as the company runs a global Phase II open-label study […]

Will TTX-MC138 in ctDNA-positive patients provide a new model for MRD intervention?

Will TTX-MC138 in ctDNA-positive patients provide a new model for MRD intervention?

TransCode Therapeutics, Inc. and Quantum Leap Healthcare Collaborative have launched a Phase 2a dose-expansion trial of TTX-MC138, an RNA-targeting therapeutic aimed at preventing metastatic recurrence in colorectal cancer patients who are ctDNA-positive after standard curative treatment. The trial is part of the PRE-I-SPY platform and will enroll up to 45 patients in early 2026, led […]