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American Society of Gene and Cell Therapy

PharmaDeviceNews American Society of Gene and Cell Therapy
A hematology specialist reviews red blood cell findings as Johnson & Johnson advances nipocalimab as a potential first targeted treatment for warm autoimmune hemolytic anemia. Representative image.
Pharma & Biotech

Vivacta and Grit Bio advance CD19-targeting CAR-T without external cell manufacturing

Vivacta Bio and Grit Bio have secured FDA orphan drug designation for GT801 in autoimmune hemolytic anemia. Early findings from two patients showed complete responses following treatment with the investigational in vivo CAR-T therapy, which uses targeted lipid nanoparticles to generate CD19-directed immune cells inside the body.

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Representative image: INOVIO Pharmaceuticals’ upcoming ASCO and ASGCT conference posters place INO-3107 DNA immunotherapy and early hemophilia A gene transfer research under the spotlight as investors watch the biotech firm’s regulatory and platform strategy.
Pharma & Biotech

INOVIO’s ASCO and ASGCT updates may sharpen scrutiny of its DNA medicine strategy

INOVIO has a regulatory clock ticking. New INO-3107 and hemophilia A data may show whether its DNA platform can move beyond promise.

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