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CAR-T

Pharma & Biotech

Moffitt Cancer Center advances Anixa ovarian CAR-T trial without dose-limiting toxicity

Anixa's ovarian cancer CAR-T inventor will deliver a November keynote as lira-cel advances through Phase 1 dose escalation. Preliminary findings include four patients surviving more than one year and an initial 90-day stable disease observation, but controlled efficacy evidence is not yet available.

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Features & Analysis

From leukapheresis to infusion: what actually happens while a patient waits for CAR-T

Conventional CAR-T therapy turns one patient’s T cells into one personalized drug batch through collection, genetic engineering, expansion, testing and release. Faster autologous, allogeneic and in-vivo approaches are trying to collapse that process from weeks toward days.

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Pharma & Biotech

Qihan Biotech gains FDA momentum for QT-019B as allogeneic CAR-T ambitions grow

Find out how Qihan Biotech’s QT-019B FDA designations could reshape autoimmune CAR-T development and what risks remain.

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Pharma & Biotech

Why Cartesian Therapeutics’ WestGene pact could intensify the race for autoimmune cell therapy

Find out how Cartesian Therapeutics’ WestGene deal could reshape in vivo CAR-T strategy in autoimmune disease and what risks remain.

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Pharma & Biotech

Gilead targets durable autoimmune remission with $2.18bn Ouro Medicines acquisition

Gilead Sciences acquires Ouro Medicines for up to $2.18bn, adding BCMA T cell engager gamgertamig to its inflammation pipeline. Analysis of what the deal reveals.

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