Hoth Therapeutics makes strategic IP move to tackle radiation and targeted therapy skin toxicities

Hoth Therapeutics makes strategic IP move to tackle radiation and targeted therapy skin toxicities

Hoth Therapeutics, Inc. has filed two provisional U.S. patents for its investigational therapy HT-001, aiming to address skin toxicities caused by radiation and targeted cancer therapies. The dual filings mark a deliberate expansion into oncology-adjacent dermatology, establishing a new intellectual property footprint around treatment-induced skin damage, including adverse effects linked to menin inhibitors. This signals […]

Takeda’s zasocitinib hits key Phase 3 psoriasis goals, challenging oral and biologic rivals

Takeda’s zasocitinib hits key Phase 3 psoriasis goals, challenging oral and biologic rivals

Takeda Pharmaceutical Company Limited has reported positive topline results from two pivotal Phase 3 studies of its investigational drug zasocitinib (TAK-279), a once-daily oral tyrosine kinase 2 (TYK2) inhibitor, in adults with moderate-to-severe plaque psoriasis. The trials met all primary and secondary endpoints, with more than 50 percent of participants achieving near-complete skin clearance (PASI […]

What the Cosette–Mayne Pharma breakdown signals for future pharma M&A in Australia

What the Cosette–Mayne Pharma breakdown signals for future pharma M&A in Australia

Cosette Pharmaceuticals, Inc. has officially terminated its proposed AUD 7.40-per-share acquisition of Mayne Pharma Group Limited after the Australian government blocked the transaction. The decision was confirmed on December 9, 2025, and followed by Mayne Pharma’s own termination notice issued on December 11. The companies cited both the Treasurer of Australia’s ruling and the expiry […]

Can Alphyn’s multi-target strategy disrupt dermatology? Why Zabalafin’s $25m backing matters

Can Alphyn’s multi-target strategy disrupt dermatology? Why Zabalafin’s $25m backing matters

Alphyn Biologics has secured $25 million in a twice-oversubscribed Series B financing round to support its clinical pipeline for dermatologic conditions. The funding will enable the company to advance a global Phase 2b trial of its lead asset, Zabalafin Hydrogel, for atopic dermatitis, while also launching a second Phase 2 program for molluscum contagiosum virus. […]