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NLRP3 inhibitor

Pharma & Biotech

How Tenvie Therapeutics is testing whether neuroinflammation can become the next obesity treatment frontier

Tenvie Therapeutics begins Phase 1 dosing of TNV262. Find out why this CNS-penetrant NLRP3 inhibitor could reshape obesity and CVD treatment.

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Pharma & Biotech

Ventyx to give Lilly an oral inflammation pipeline—what’s the real upside?

Eli Lilly and Company has announced plans to acquire Ventyx Biosciences Inc. in an all-cash transaction valued at approximately $1.2 billion, securing a portfolio of clinical-stage oral small molecule therapeutics focused on chronic inflammatory-mediated diseases. The deal includes NLRP3 inhibitors such as VTX2735 and VTX3232, alongside two Phase 2 programs for inflammatory bowel disease. The

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