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Home»Posts tagged with»preclinical data

What Caliway’s CBL-514 and tirzepatide combination data could reveal about obesity treatment next

By Pallavi Madhiraju on April 5, 2026   Pharma & Biotech  

What Caliway’s CBL-514 and tirzepatide combination data could reveal about obesity treatment next

Caliway’s CBL-514 heads to ADA 2026 with tirzepatide combination data. Read what this could change in obesity treatment strategy.

How Orum Therapeutics plans to solve GSPT1 toxicity with a DAC approach in AML

By Pallavi Madhiraju on March 19, 2026   Pharma & Biotech  

How Orum Therapeutics plans to solve GSPT1 toxicity with a DAC approach in AML

Orum Therapeutics presents ORM-1153 DAC preclinical data at AACR 2026, including primate safety findings ahead of a planned AML IND filing. Read the analysis.

Can CRISPR editing of NRF2 reverse resistance in head and neck squamous cell carcinoma?

By Pallavi Madhiraju on January 24, 2026   Pharma & Biotech  

Can CRISPR editing of NRF2 reverse resistance in head and neck squamous cell carcinoma?

CorriXR’s new data show CRISPR-based NRF2 disruption restores chemo response in squamous tumors. Find out what this could mean for HNSCC treatment.

Can TN-001 avoid hallucinogenic pitfalls while delivering rapid antidepressant effects?

By Pallavi Madhiraju on January 15, 2026   Pharma & Biotech  

Can TN-001 avoid hallucinogenic pitfalls while delivering rapid antidepressant effects?

Transneural’s TN-001 shows rapid neuroplasticity without hallucinogenic effects. Find out what this could mean for MDD and PTSD treatment strategies.

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