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apolipoprotein C-III

Pharma & Biotech

Ionis TRYNGOLZA wins EU recommendation after 85% reduction in pancreatitis events

European regulators have recommended extending TRYNGOLZA to adults with fasting triglycerides of at least 880 mg/dL. The decision follows two Phase 3 trials demonstrating substantial triglyceride reductions and 85% fewer adjudicated acute pancreatitis events in a pooled analysis.

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Pharma & Biotech

Is Arrowhead’s plozasiran becoming the RNAi drug to watch in extreme triglyceride disorders?

Arrowhead’s plozasiran data ease dosing concerns in complex patients, but Phase 3 results will decide its broader triglyceride market role.

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Pharma & Biotech

Arrowhead’s plozasiran clears CHMP: what a positive opinion for FCS means for siRNA’s regulatory arc in Europe

Plozasiran clears CHMP but the real test is reimbursement. Europe's HTA bodies will now decide whether clinical FCS diagnosis is enough.

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