Can Ascletis ASC30 compete with established oral GLP-1 treatments?
Ascletis reports up to 1.7-point HbA1c reduction and 4.4% weight loss with oral ASC30, as larger trials must confirm safety and efficacy.
Ascletis reports up to 1.7-point HbA1c reduction and 4.4% weight loss with oral ASC30, as larger trials must confirm safety and efficacy.
Ascletis Pharma has dosed the first participant in a 4,600-person global Phase 3 program for ASC30, a once-daily oral small-molecule GLP-1 receptor agonist that produced up to 7.7% placebo-adjusted weight loss after 13 weeks in Phase 2.
Oral GLP-1s promise convenience, but proof is still clinical. Ascletis’ ASC30 diabetes trial could test whether hype can meet HbA1c data.
Ascletis starts U.S. Phase II trial of ASC30 in type 2 diabetes. Find out what this oral GLP-1R agonist could mean for the future of metabolic therapies.