Kallisio’s Stentra system enters clinical use at Stanford, expanding precision radiation toolkit for head and neck cancer

Kallisio’s Stentra system enters clinical use at Stanford, expanding precision radiation toolkit for head and neck cancer

Kallisio has begun clinical implementation of its FDA-cleared Stentra system at Stanford Health Care, marking the first reported integration of the patient-specific intraoral device into a major U.S. hospital’s workflow for head and neck cancer radiation therapy. The system, which received 510(k) clearance in January 2024, enables individualized immobilization of oral structures during intensity-modulated radiation […]

Privo’s PRV131 enters first-in-human dosing: Can injectable cisplatin change oral cancer surgery?

Privo’s PRV131 enters first-in-human dosing: Can injectable cisplatin change oral cancer surgery?

Privo Technologies has officially initiated dosing in a Phase 1/2 trial evaluating PRV131, its nanoengineered intratumoral cisplatin injectable, for the treatment of T1–T3 oral squamous cell carcinoma (OSCC). The trial, designated Arm 3 of the CLN-004 study, will explore PRV131 as a neoadjuvant therapy aimed at shrinking tumors before surgery. The announcement marks a pivotal […]

Proton therapy delivers survival gain in head and neck cancer: Could this Lancet trial shift payer and policy resistance?

Proton therapy delivers survival gain in head and neck cancer: Could this Lancet trial shift payer and policy resistance?

A new phase III clinical trial published in The Lancet has shown that proton therapy significantly improves overall survival and reduces treatment-related toxicities in patients with oropharyngeal cancers compared to traditional photon-based radiation. Conducted across 21 U.S. institutions and led by researchers at the University of Texas MD Anderson Cancer Center, the study is the […]