Cereno Scientific’s CS014 shows antithrombotic effect without bleeding risk in new HDAC study

Cereno Scientific’s CS014 shows antithrombotic effect without bleeding risk in new HDAC study

Cereno Scientific has announced the peer-reviewed publication of its next-generation HDAC inhibitor CS014 in the Journal of Thrombosis and Haemostasis, revealing the compound’s ability to significantly reduce thrombosis without increasing bleeding risk. The study marks the first formal disclosure of CS014’s chemical structure and nonclinical pharmacology, positioning the compound as a differentiated HDAC inhibitor with […]

Boehringer Ingelheim expands Jascayd label to PPF following pivotal trial success

Boehringer Ingelheim expands Jascayd label to PPF following pivotal trial success

Boehringer Ingelheim has secured approval from the United States Food and Drug Administration for Jascayd (nerandomilast) tablets for the treatment of progressive pulmonary fibrosis in adults. The decision follows earlier FDA clearance for Jascayd in idiopathic pulmonary fibrosis and now marks the first time a preferential PDE4B inhibitor with dual immunomodulatory and antifibrotic effects has […]