Can TCR bispecifics unlock prostate cancer immunotherapy? Why Pfizer is backing Flagship and Repertoire

Can TCR bispecifics unlock prostate cancer immunotherapy? Why Pfizer is backing Flagship and Repertoire

Flagship Pioneering has launched a new research program with Pfizer through its portfolio company Repertoire Immune Medicines, focused on the development of T cell receptor (TCR) bispecifics for metastatic prostate cancer. This marks the eighth initiative under the broader Flagship–Pfizer strategic alliance. The program will harness Repertoire’s DECODE platform to map immune synapse interactions and […]

Can anti-TFPI drugs like HYMPAVZI reshape the standard of care in inhibitor-positive hemophilia?

Can anti-TFPI drugs like HYMPAVZI reshape the standard of care in inhibitor-positive hemophilia?

Pfizer Inc. has moved a step closer to reshaping the treatment paradigm for one of hemophilia’s most challenging patient subgroups. The company’s investigational therapy HYMPAVZI (marstacimab) demonstrated a 93 percent reduction in bleeding episodes in patients with hemophilia A or B who have developed inhibitors, according to data presented at the 67th American Society of […]