Can Diakonos Oncology’s DOC1021 reawaken immune response in refractory melanoma?

Can Diakonos Oncology’s DOC1021 reawaken immune response in refractory melanoma?

Diakonos Oncology Corporation has received over $7 million from the Cancer Prevention and Research Institute of Texas to initiate a Phase 1/2 clinical trial of its double-loaded dendritic cell therapy, DOC1021, in patients with refractory melanoma. The grant places the investigational therapy into its third solid tumor indication and signals rising institutional interest in immune-based […]

Can Senhwa’s CX-5461 finally turn cold tumors hot in immunotherapy’s toughest challenge?

Can Senhwa’s CX-5461 finally turn cold tumors hot in immunotherapy’s toughest challenge?

Senhwa Biosciences Inc. and BeOne Medicines have signed a clinical supply agreement to explore a novel drug combination aimed at treating hard-to-reach cancers. The collaboration will test Senhwa’s lead compound Pidnarulex (CX-5461), a G-quadruplex stabilizer, in combination with BeOne’s PD-1 inhibitor tislelizumab. The Phase 1b/2a clinical trial will enroll patients with advanced solid tumors, including […]