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severe hypertriglyceridemia

Pharma & Biotech

Ionis Pharmaceuticals moves beyond rare disease as Tryngolza enters the wider triglyceride market

Tryngolza is no longer confined to the rare familial chylomicronemia syndrome market. Its broader United States approval gives clinicians the first therapy specifically shown to reduce acute pancreatitis risk in adults with severe hypertriglyceridemia, although questions surrounding dose selection, hepatic monitoring, reimbursement and long-term use will influence how quickly the treatment changes practice.

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Pharma & Biotech

OrsoBio’s TLC-2716 data point to a new oral route in severe metabolic lipid disease

Find out how OrsoBio’s TLC-2716 Phase 2a data could reshape severe hypertriglyceridemia and MASLD drug development.

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Pharma & Biotech

Is Arrowhead’s plozasiran becoming the RNAi drug to watch in extreme triglyceride disorders?

Arrowhead’s plozasiran data ease dosing concerns in complex patients, but Phase 3 results will decide its broader triglyceride market role.

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Pharma & Biotech

Can Arrowhead Pharmaceuticals expand plozasiran without the Ionis patent fight becoming a commercial overhang?

Arrowhead Pharmaceuticals is advancing plozasiran fast, but can it overcome the Ionis patent dispute? Read the deeper legal and commercial analysis.

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Pharma & Biotech

Arrowhead Pharmaceuticals strengthens plozasiran’s severe hypertriglyceridemia case with durable ACC.26 data

Arrowhead Pharmaceuticals’ plozasiran posted durable triglyceride reductions at ACC.26. Read what the long-term data could change next.

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